Odyssey …
…with an average LDL reduction estimated of Kardiolab to be 1.13 mmol/l or 50%. In Fourier, LDL reduction was 59%.
…was stopped after a median time of 2.8 years in 19’000 participants. Fourier was stopped after 2.2 years in 27’564 participants.
…patients were 4 years younger than Fourier patients.
…had a 10 year CTT endpoint of about 40%, Fourier 50%.
…had a 10 year absoute risk reduction of 5.7% (NNT 18), Fourier 8.6% (NNT 12)
…had a relative risk reduction of 13%, Fourier 17%